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Успехи современной биологии, 2023, T. 143, № 5, стр. 487-505

rol-гены агробактерий: возможные биологические функции

Д. Ю. Швец 1, 2, *, З. А. Бережнева 1, Х. Г. Мусин 1, Э. А. Баймухаметова 1, Б. Р. Кулуев 1

1 Институт биохимии и генетики – обособленное структурное подразделение Уфимского федерального исследовательского центра Российской академии наук
Уфа, Россия

2 Башкирский государственный медицинский университет
Уфа, Россия

* E-mail: shvetsdasha99@yandex.ru

Поступила в редакцию 25.03.2023
После доработки 02.05.2023
Принята к публикации 03.05.2023

Аннотация

Гены rolA, rolB, rolC и rolD Agrobacterium rhizogenes, встраиваясь в геномы растений в составе Т-ДНК при агробактериальной трансформации, обусловливают обильное разрастание волосовидных корней, а при регенерации из них побегов приводят к низкорослости, укорочению междоузлий и формированию морщинистых листьев. Ряд представителей родов Nicotiana, Linaria, Ipomoea и других в своем геноме содержат некоторые rol‑гены, которые попали в них при горизонтальном переносе генов и эволюционно закрепились. Тот факт, что как в A. rhizogenes, так и в природно-трансгенных растениях rol-гены консервативны, может говорить о выполнении ими важных биологических функций. Целью данной обзорной статьи является рассмотрение имеющихся на сегодняшний день данных о биологической роли rol-генов в волосовидных корнях, трансформированных и природно-трансгенных растениях. На сегодняшний день показано, что экспрессия rol-генов как вместе, так и по отдельности оказывает различное влияние на морфологию как трансформированных агробактериями растений, так и природно-трансгенных видов. В обзоре представлены результаты исследований, показавшие позитивное влияние rol-генов на вторичный метаболизм, антиоксидантную систему и стрессоустойчивость растений. Также обсуждается вопрос о возможном действии белковых продуктов rol-генов через влияние на содержание фитогормонов или чувствительности к ним. Описываются экспериментальные свидетельства о ферментативной активности Rol-белков по отношению к глюкозидам фитогормонов, а также субклеточная локализация Rol-белков. Однако эти эксперименты не дали исчерпывающих ответов, поэтому исследования биологических функций rol-генов должны быть продолжены, так как полученные при этом знания могут быть использованы при создании трансгенных и редактированных растений с хозяйственно-ценными признаками.

Ключевые слова: волосовидные корни, rol-гены, Agrobacterium rhizogenes, plast-гены, стрессоустойчивость

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